Dual-radiolabeled nanoparticle SPECT probes for bioimaging
نویسندگان
چکیده
منابع مشابه
Dual-radiolabeled nanoparticle SPECT probes for bioimaging.
A gold nanoparticle was radiolabeled with (125)I and (111)In and functionalized with an MMP9-cleavable peptide to form a multispectral SPECT imaging contrast agent. Peptide cleavage from the nanoprobe by MMP9 was observed in vitro, and distinct pharmacokinetic properties of the contrast agent were observed between tumors with high or low MMP9 expression.
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ژورنال
عنوان ژورنال: Nanoscale
سال: 2015
ISSN: 2040-3364,2040-3372
DOI: 10.1039/c4nr05269b